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Boost Your Glow: The Benefits of Microneedling with PRP, Exosomes & PDRN (Salmon DNA)


At Skin + Body by Smooth Med in Burbank, we love helping our clients achieve radiant, youthful skin using the latest regenerative aesthetics. One of our most powerful skin-rejuvenating treatments is microneedling—but did you know that pairing it with the right booster serum can take your results to the next level?


Today, we’re breaking down the benefits and differences between Microneedling with PRP, Exosomes, and PDRN (salmon DNA) so you can make the best choice for your skin goals.

What Is Microneedling?

Microneedling is a collagen-induction therapy that uses tiny needles to create controlled micro-injuries on the skin’s surface. These microchannels kickstart your skin’s natural healing process, boosting collagen and elastin production to improve texture, tone, and radiance.

When paired with advanced serums like PRP, Exosomes, or PDRN, the healing response is amplified, allowing active ingredients to penetrate the skin deeply for even more impressive results.


Option 1: Microneedling with PRP (Platelet-Rich Plasma)

What it is: PRP is a healing serum derived from your blood. After a quick blood draw, we spin it in a centrifuge to separate the golden plasma rich in growth factors. This is then microneedled into the skin.

Why clients love it:

  • Natural and safe—uses your own body's healing properties

  • Stimulates collagen and elastin

  • It helps fade acne scars, smooth texture, and even skin tone

  • It can reduce redness, inflammation, and dark under-eye circles

Ideal for: Those wanting a natural approach to skin rejuvenation and collagen stimulation, especially if dealing with scarring or early signs of aging.


Option 2: Microneedling with Exosomes

What it is: Exosomes are cutting-edge regenerative messengers derived from stem cells. They contain peptides, growth factors, amino acids, and RNA—everything your skin needs to repair and renew.

Why clients love it:

  • Accelerates healing and recovery

  • More powerful collagen stimulation than PRP

  • Improves pigmentation, fine lines, and dullness

  • Helps repair skin at a cellular level

Ideal for: Clients seeking the most advanced anti-aging results or those wanting faster healing and enhanced skin texture and brightness.


Option 3: Microneedling with PDRN (Salmon DNA)

What it is: PDRN (Salmon DNA) is a naturally occurring compound derived from purified salmon sperm DNA. It has remarkable regenerative and anti-inflammatory properties and is well tolerated by the skin.

Why clients love it:

  • Deep hydration and barrier repair

  • Reduces redness and inflammation

  • Helps with fine lines, crepey skin, and skin thinning

  • Promotes cell regeneration and DNA repair

Ideal for: Anyone with sensitive, dehydrated, or inflamed skin or those looking for gentle anti-aging support and overall skin health.


Which Option Is Right for You?

Here’s a quick guide to help you decide:

Skin Concern

Best Choice

Acne scars, texture, dullness

PRP

Advanced aging, pigmentation, fast healing

Exosomes

Sensitive skin, redness, dehydration

PDRN (Salmon DNA)

Still unsure? We offer personalized skin consultations to help you choose the best treatment for your unique skin type and goals.


Ready to Experience the Power of Regenerative Microneedling?

At Skin + Body by Smooth Med, we’re proud to offer all three of these advanced microneedling options. Whether you’re looking for a natural glow, deep hydration, or age-defying results, we’ve got a solution designed just for you.


📍 Visit us in Burbank or call/text to schedule your consultation.


Let’s build your best skin—one treatment at a time.



 
 
 

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